时间域和扫描源全场的快速光谱塑造,OCT
Dimitri Roueff1, Pedro Mecê1, Olivier Thouvenin1
1Institut Langevin, ESPCI Paris, Université PSL, CNRS, 75005 Paris, France.
Biomedical optics express
|November 27, 2025
概括
研究人员开发了一种全场光学连贯断层扫描 (FFOCT) 的新型光谱成型方法. 这项创新使灵活的波长选择和高分辨率成像成为可能,克服了FFOCT系统当前的局限性.
科学领域:
- 生物医学光学 生物医学光学
- 在光学成像系统中,光学成像
- 医学物理 医学物理
背景情况:
- 全场光学连贯断层扫描 (FFOCT) 正在获得引力,这是由于OCT动态和扫描源的进步.
- 当前的FFOCT系统在波长选择和轴分辨率方面存在局限性,这限制了它们的应用.
- 需要更具多功能性和更高分辨率的FOCT成像解决方案.
研究的目的:
- 开发一种用于FFOCT成像中的快速光谱成形的新方法.
- 为了创建一个与FFOCT系统兼容的灵活光源.
- 为了提高FFOCT中的轴分辨率和成像速度.
主要方法:
- 一个超连续激光器与一个快速的声光调节过器 (AOTF) 结合起来.
- 用于光谱成型,使用了具有被动和主动模式混合的多模纤维.
- 调整了AOTF频率以产生所需的光谱 (575-1000 nm) 来进行时间域FFOCT或扫描源FFOCT.
主要成果:
- 成功开发了一种与FFOCT兼容的极其灵活的光源.
- 该方法允许在575-1000nm范围内创建任何感兴趣的频谱.
- 实现了高达100kfps的扫源FFOCT,轴分辨率为1.1μm.
结论:
- 开发的光谱造型方法显著提高了FFOCT光源的灵活性.
- 这种技术克服了FFOCT波长选择和轴分辨率的局限性.
- 该系统可实现高速,高分辨率的FFOCT成像,为应用开辟了新的可能性.
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