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Updated: Jul 29, 2026

In Vivo Methods to Assess Retinal Ganglion Cell and Optic Nerve Function and Structure in Large Animals
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斑点白点病变与高反射光学连贯性断层扫描在Cynomolgus和 rhesus子中的发现

Tomoaki Araki1, Masamitsu Shimazawa2,3, Shinsuke Nakamura2

  • 1Shin Nippon Biomedical Laboratories Ltd. Drug Safety Research Laboratories (SNBL DSR), Kagoshima, Japan.

Molecular vision
|November 27, 2025
PubMed
概括

研究人员在Cynomolgus和 rhesus的斑点中发现了白点 (WDs). 这些发现表明有可能发展黄斑变性,表明未来研究的可能动物模型.

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Phase Contrast and Differential Interference Contrast Microscopy01:26

Phase Contrast and Differential Interference Contrast Microscopy

Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...