探索黑素在减轻乳腺癌幸存者的更年期症状中的有效性:一项随机,双盲,安慰剂控制的随机研究
Parinaz Sattari1, Melika Shakourifar1, Khatereh Jafarian1
1Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
Advanced biomedical research
|November 27, 2025
概括
在接受抗激素治疗的乳腺癌患者中,补充黑素显著降低了热和更年期症状. 这种治疗也改善了生活质量和性功能,这表明黑激素是乳腺癌治疗的有益补充.
科学领域:
- 在瘤学瘤学.
- 内分泌学 在内分泌学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 接受抗激素治疗的荷尔蒙阳性乳腺癌 (BC) 患者经历更年期症状,如发热和情绪变化.
- 黑色素在缓解绝经后妇女的绝经症状方面表现有前途.
- 这项研究研究了黑激素在治疗BC患者治疗诱导更年期的疗效.
研究的目的:
- 评估黑素补充剂对接受抗激素药物治疗的乳腺癌患者更年期并发症的影响.
- 评估黑激素对热,生活质量和性功能在这个患者群体的影响.
主要方法:
- 一年期,随机的,安慰剂控制的临床试验,涉及成年BC患者,在服用抗激素药物时出现更年期症状.
- 参与者每天两次口服3毫克黑激素或安慰剂,持续四周.
- 标准化问卷 (更年期评分表,更年期特定的生活质量,女性性功能指数) 用于评估.
主要成果:
- 60名患者完成了为期四周的研究,没有显著的基线差异.
- 补充黑素导致热的频率和严重程度显著降低.
- 接受黑色素治疗的患者报告生活质量和性功能得分有所改善.
结论:
- 黑色素有效地改善更年期症状,提高生活质量,改善乳腺癌患者接受抗激素治疗的性功能.
- 黑色素显示出作为治疗诱导的更年期在乳腺癌患者管理的辅助疗法的潜力.
- 进一步的研究可能会支持将黑激素纳入这些患者的标准护理方案.
更多相关视频
09:25The Treadmill Fatigue Test: A Simple, High-throughput Assay of Fatigue-like Behavior for the Mouse
Published on: May 31, 2016
19.9K
04:59Heat-sensitive Moxibustion as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Insomnia
Published on: May 30, 2025
1.2K
相关概念视频
Management of Insomnia
507
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
507
Menopause
3.5K
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
3.5K
The Placebo Effect
6.8K
The placebo effect occurs when people's expectations or beliefs influence or determine their experience in a given situation. In other words, simply expecting something to happen can actually make it happen.
6.8K
