患有OSAS的个体中抑郁症的预测因素:土耳其的横截面研究
1Department of Chest Diseases, Çorum Hitit University Faculty of Medicine, Çorum, Türkiye.
Nigerian journal of clinical practice
|November 27, 2025
概括
抑郁症在阻塞性睡眠呼吸暂停综合征 (OSAS) 中很常见. 睡眠质量差和女性性别预测OSAS患者的抑郁症,而不是低氧症负担.
科学领域:
- 睡眠医学 睡眠医学
- 精神病学是一个精神病学.
- 肺部病理学 肺部病理学
背景情况:
- 阻塞性睡眠呼吸暂停综合征 (OSAS) 通过神经炎症,神经递质变化和睡眠不良与抑郁症有关.
- 睡眠模式的改变可能表明OSAS患者的抑郁症.
研究的目的:
- 为了确定OSAS患者抑郁症状的患病率.
- 为了检查抑郁症症状,过度白天嗜睡 (ES),睡眠质量和OSAS中的低氧症之间的关联.
主要方法:
- 150名新诊断的OSAS患者接受了多睡眠扫描 (PSG).
- 患者完成了爱普沃思睡眠度量表 (ESS),老年抑郁度量表 (GDS-LF) 和匹兹堡睡眠质量指数 (PSQI).
- 低氧症是通过氧和率<90% (TST 90) 的时间来评估的.
主要成果:
- 84%的人报告睡眠质量不佳;45.3%的人有抑郁症状.
- 多变量分析确定了女性性别和更高的PSQI得分作为抑郁症的独立预测因素.
- 呼吸暂停-呼吸暂停指数 (AHI) 和低血压负担并不是显著的预测因素.
结论:
- 睡眠质量差和女性性别是OSAS中抑郁症的关键预测因素.
- 评估和管理睡眠质量,特别是女性OSAS患者,对于改善心理健康至关重要.
- 在这个队列中,AHI和低氧化负担与抑郁症没有显著的关联.
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