孤立的 (非) 社会大脑
A Fishman1, P Grinin, V Riljak
1Institute of Physiology of the First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic. vladimir.riljak@lf1.cuni.cz.
Physiological research
|November 27, 2025
概括
社会孤立 (SI) 损害了社会大脑,作为慢性压力. 这份综述表明,SI破坏了社会认知,增加了精神和神经退行性疾病的风险.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 预防医学 预防医学
背景情况:
- 社会大脑网络对于社会认知,同情和行为至关重要.
- 社会孤立 (SI) 客观地减少了社会互动,威胁到社会大脑的完整性.
- 情绪系统作为一种慢性压力因素,具有显著的神经生物学和行为后果.
研究的目的:
- 审查关于SI对社会大脑的生物学,认知和行为影响的证据.
- 阐明SI如何破坏神经解剖学,神经递质和社会功能.
- 突出SI作为跨多个医学领域的跨诊断风险因素.
主要方法:
- 综合来自人类和动物研究的证据.
- 由于SI而导致的神经解剖学和神经化学变化的审查.
- 在动物和灵长类动物模型中检查进化保存机制.
主要成果:
- SI破坏了对社会认知至关重要的结构连接和神经递质系统.
- SI导致改变了社会行为,心态化和情绪反应.
- 它会影响神经发育,神经可塑性,并引发不适应性应激反应.
结论:
- SI显著增加了对精神病和神经退行性疾病的脆弱性.
- 间接的压力因素,如缺少触摸,可以放大SI的神经生物学影响.
- 解决SI对于心理性和福祉至关重要,特别是在流行病后.
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