来自阿尔及利亚生态系统的新型乳酸细菌的表征,具有益生菌潜力和抗氧化剂-抗糖尿病特性
Abdelkader Mahrouk1,2, Asma Mosbah1, Noreddine Kacem Chaouche3
1Laboratory of Applied Biochemistry, Faculty of Natural and Life Sciences, University Constantine 1, Constantine, 25000, Algeria.
Folia microbiologica
|November 27, 2025
概括
来自阿尔及利亚生态系统的益生菌显示出抗氧化和抗糖尿病的潜力. 这些乳酸细菌菌株有效地清除自由基并抑制α-氨酶酶,为管理氧化应激和糖尿病提供了希望.
科学领域:
- 微生物学 微生物学
- 生物化学 生化学
- 食品科学 食品科学 食品科学
背景情况:
- 益生菌提供健康益处,包括抗氧化和抗糖尿病作用.
- 乳酸细菌是益生菌菌株的常见来源.
- 阿尔及利亚的生态系统是新型益生菌发现的多样化来源.
研究的目的:
- 从阿尔及利亚生态系统中分离和描述乳酸细菌.
- 评估孤立菌株的抗氧化和抗糖尿病潜力.
- 识别有前途的益生菌候选人用于健康应用.
主要方法:
- 从阿尔及利亚各个生态系统中分离出54种乳酸细菌菌株.
- 在体外评估抗氧化剂活性 (DPPH,ABTS•+,FRAP测试).
- 对α-氨酶抑制的评估,益生菌特性 (pH,盐,胆汁耐受性) 和安全性 (血液溶解活性).
主要成果:
- 十种菌株显示出显著的益生菌潜力,包括对低pH,NaCl和胆汁盐的耐药性.
- 所有孤立的菌株都表现出强大的抗氧化能力,清除DPPH和ABTS•+基.
- 选择的菌株显示出高水性,聚合性和抗菌活性,没有血液溶解作用.
结论:
- 来自阿尔及利亚生态系统的确定的益生菌菌株具有显著的抗氧化和抗糖尿病特性.
- 这些菌株是开发功能性食品和补充剂的有希望的候选人,以对抗氧化应激和糖尿病.
- 需要进一步的体内研究来证实这些新型益生菌的治疗疗效.
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