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相关概念视频

Biological Causes of Schizophrenia01:29

Biological Causes of Schizophrenia

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Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
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Human Genetics01:28

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Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
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相关实验视频

Updated: Jan 6, 2026

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration
04:41

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration

Published on: January 9, 2020

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门德尔随机化分析支持COVID-19与大脑结构和功能变化之间的因果关系.

Qitong Wang1, Fang Liu1, Xinyu Wang1

  • 1Department of Neurology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, 570311, Hainan, China.

European archives of psychiatry and clinical neuroscience
|November 27, 2025
PubMed
概括

这项研究使用了门德尔的随机化来调查COVID-19和大脑变化之间的因果关系. 研究结果表明,COVID-19,脑成像表型和神经心理症状之间存在弱因果关系.

关键词:
大脑雾是什么?大脑雾是什么?在 COVID-19 疫情中,这就是为什么MRI是MRI.神经成像是一种神经成像.神经心理学 神经心理学在COVID后的病情.

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Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
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Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

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Brain Imaging Investigation of the Neural Correlates of Observing Virtual Social Interactions
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Brain Imaging Investigation of the Neural Correlates of Observing Virtual Social Interactions

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Last Updated: Jan 6, 2026

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科学领域:

  • 神经科学是一个神经科学.
  • 遗传学 遗传学 是一个
  • 传染性疾病 传染性疾病

背景情况:

  • 脑雾等神经精神症状在COVID-19后很常见.
  • 这些症状背后的生物学机制尚不清楚.
  • 以前的观察性研究表明与大脑变化的联系,但因果关系仍然不确定.

研究的目的:

  • 探索COVID-19和脑成像衍生的表型 (IDP) 之间的潜在因果关系.
  • 为了调查COVID-19和神经心理症状之间的因果关系.
  • 评估COVID-19对大脑结构和功能的影响.

主要方法:

  • 利用了全基因组关联研究 (GWAS) 的总结统计数据.
  • 进行了两个样本的门德尔随机化 (MR) 分析.
  • 包括敏感性分析,以确保结果的可靠性.

主要成果:

  • 确定了COVID-19和22个皮质结构表型,一个皮质下大脑结构表型和五个大脑功能网络表型之间的因果关系.
  • 发现了COVID-19和一个神经心理症状表型之间的因果关系.
  • 观察到COVID-19和确定的大脑表型之间的主要负相关性.

结论:

  • 表明COVID-19和脑成像衍生的表型 (IDP) 之间存在弱因果关系.
  • 这表明COVID-19和神经心理症状之间存在潜在的因果关系.
  • 强调需要进一步的研究来验证这些关联,并了解潜在的机制.