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在六个机构的化疗和手术患者中,自我报告的整体幸福感和身体功能
Michael J Hassett1, Christine M Cronin1, Angela C Tramontano1
1Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
Cancer
|November 27, 2025
概括
整体健康 (OWB) 和身体功能 (PFN) 的单项测量可以有效地补充癌症护理中的电子患者报告结果 (ePRO). 这些简短的评估与症状相关,并预测临床结果,有助于患者管理.
科学领域:
- 在瘤学瘤学.
- 数字健康数字健康
- 患者报告的结果
背景情况:
- 电子患者报告结果 (ePRO) 对于管理癌症患者的症状负担至关重要.
- 这项研究研究了两个单项生活质量指标的实用性:整体福祉 (OWB) 和身体功能 (PFN).
- 假设是OWB和PFN可以提供独特的,有价值的信息来增强标准的ePRO.
研究的目的:
- 评估单项整体健康 (OWB) 和身体功能 (PFN) 的测量是否可以补充癌症护理中的多项ePRO.
- 识别与OWB和PFN相关的特征.
- 描述OWB/PFN,症状负担和临床结果之间的相关性.
主要方法:
- 在六个机构中使用了eSyM电子症状管理程序.
- 为胸部,胃肠道或妇科恶性瘤接受化疗或手术的患者每周填写问卷,包括12个症状项目和OWB和PFN的单个项目.
- 统计分析描述了OWB/PFN,症状和临床结果之间的关联.
主要成果:
- 在2019年9月至2024年2月期间,超过1万名患者提交了78,000多份问卷.
- 大多数患者报告了OWB和PFN的轻微损伤.
- OWB和PFN显示了彼此的中等相关性,总症状负担,疼痛,疲劳,食欲,并与急诊,入院和生存相关.
结论:
- 自我报告的OWB和PFN显示了歧视性和面部有效性,与常见症状和临床结果相关.
- 这些单项措施通过将症状报告置于背景中来补充多项调查问卷.
- OWB和PFN作为简短的选,以识别癌症患者有严重症状或不良结果的风险,指导管理.
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