从功能性食品中选择性化物提取,通过量身定制的深度性溶剂-性电解水系统
Fuhui Luo1, Zhongqiao Zhao1, Yong He1
1Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Guangxi Key Laboratory of Chemistry and Molecular Engineering of Medicinal Resources, University Engineering Research Center for Chemistry of Characteristic Medicinal Resources (Guangxi), School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin 541004, PR China.
Food chemistry
|November 27, 2025
概括
一种新型的性电解水和深溶解剂溶解剂 (AEWDES) 系统增强了从Nelumbinis Plumula中提取类化合物的效果. 这种由CPO-BP-SSA优化的绿色方法,显示出生物活性化合物回收的卓越效率和可持续性.
科学领域:
- 植物化学 植物化学
- 绿色化学 绿色化学
- 生物技术是生物技术.
背景情况:
- 梅花 Nelumbinis 是一种有价值的药用和食用植物,具有显著的制药潜力.
- 生物活性化合物,特别是类化合物,是其治疗性质的关键.
- 需要有效和可持续的提取方法来利用这些化合物.
研究的目的:
- 开发一种新的,高效和可持续的溶剂系统,用于从Nelumbinis Plumula中提取类化合物.
- 使用混合计算框架优化提取过程.
- 评估开发方法的绿色指标和普遍性.
主要方法:
- 开发了一种新的性电解水和深度浸泡溶剂 (AEWDES) 系统.
- 对30种溶剂进行选,确定L-proline-1-methylurea (LP-JJN) 是最佳的.
- 采用Crested porcupine优化器-反向传播神经网络-Sparrow搜索算法 (CPO-BP-SSA) 进行提取优化.
- 对超声波辅助的DES和传统溶剂进行提取效率的评估.
主要成果:
- 与其他方法相比,开发的AEWDES (LP-JJN) 显示出更高的提取效率.
- 产量增强归因于AEWDES介导的细胞壁破坏和改善的分子间相互作用.
- 绿色指标证实了AEWDES提取方法的可持续性.
- 该CPO-BP-SSA框架有效优化了化物提取过程.
结论:
- 新的AEWDES提取系统提供了一种高效和可持续的方法,用于从Nelumbinis Plumula中回收化物.
- 这种方法为提取各种类化合物提供了通用参考.
- 未来的工作应该专注于类化合物回收的先进技术.
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