听力损失事件发生前后抑郁症状的发展轨迹:一项为期24年的基于人口的纵向队列研究
Qin Li1, Haohong Lai2, Juntao Wu3
1Department of Hearing and Speech-Language Science, Guangzhou Xinhua University, 19 of Hua Mei Road, Guangzhou 510520, China; Department of Otolaryngology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107th Yanjiangxi Road, Guangzhou, Guangdong 510120, China.
Archives of gerontology and geriatrics
|November 27, 2025
概括
新的听力损失 (HL) 与抑郁症状的立即和长期增加有关. 早期听力检测和干预对于预防老年人晚年抑郁症至关重要.
科学领域:
- 老年学是一门学科.
- 流行病学 流行病学
- 精神病学是一个精神病学.
背景情况:
- 听力损失 (HL) 是抑郁症状的一个已知的危险因素.
- 听力损失开始后抑郁症状的进展情况尚不清楚.
- 这项研究调查了事件听力损失和抑郁症状的轨迹之间的关联.
研究的目的:
- 为了确定事件听力损失是否与抑郁症状的急性增加有关.
- 检查事件听力损失是否与随着时间的推移持续的抑郁症状进展有关.
- 在听力损失发生之前,要考虑先前存在的抑郁症状轨迹.
主要方法:
- 利用了来自健康和退休研究 (1998-2022) 的纵向数据.
- 评估每两年一次的抑郁症状,使用8项的流行病学研究中心抑郁症量表 (CES-D).
- 采用线性混合效应模型来分析听力损失发作后抑郁症状的急性和年度变化,以基线共变量和HL前轨迹进行调整.
主要成果:
- 该研究包括11,099名参与者,平均年龄为64.8岁;3024人患有事件性听力损失.
- 两组之间没有观察到HL前每年抑郁症状增加的显著差异.
- 在听力损失发作后,发现抑郁症状显著急剧增加 (β = 0.234) 和持续每年加速 (β = 0.013/年).
结论:
- 事件性听力损失与抑郁症状的立即增加和长期进展有关.
- 这些影响独立于听力损失发作之前的抑郁症状轨迹.
- 强调听力损失是晚年抑郁症的可预防风险因素,强调早期发现和干预.
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