韩国成年人周末追赶睡眠和白细胞计数之间的关联:基于人口的横截面研究
Juyeon Lee1, Ye-Jee Kim2, Bo Ram Yang3
1Senior Health Convergence Research Center based on Life Cycle, Daejeon, Republic of Korea; College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea.
Preventive medicine
|November 27, 2025
概括
长时间的周末追赶睡眠 (WCS) 与较高的白细胞 (WBC) 数量有关,这表明炎症增加. 定期,适度的睡眠模式可以帮助减少全身炎症.
科学领域:
- 睡眠医学 睡眠医学
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
背景情况:
- 通过血清白细胞 (WBC) 计数表示的系统性炎症是各种慢性疾病的危险因素.
- 周末追赶睡眠 (WCS) 是一种常见的行为,但其与全身炎症的关联仍然不清楚.
研究的目的:
- 为了研究周末追赶睡眠 (WCS) 和全身炎症 (血清WBC计数) 之间的关联.
主要方法:
- 韩国国家健康和营养检查调查 (2016-2018,2021) 的22,143名参与者的横截面研究.
- 参与者分为没有WCS (<1小时),中度WCS (1至3小时) 和延长WCS (≥3小时).
- 多种逻辑回归用于评估WCS和WBC计数之间的关联,对年龄,性别,BMI,睡眠时间和睡前不一致性进行分层分析.
主要成果:
- 延长的WCS与较高的WBC数量相对应,特别是在年轻的成年人 (20-39岁),男性,BMI<25 kg/m2的个体和不规则的睡觉时间的人中.
- 根据年龄,性别,BMI和睡前不一致性观察到显著的相互作用.
- 中度WCS显示与较高的BMI有相反的关联.
结论:
- 延长WCS与特定亚组的系统性炎症升高有关.
- 保持定期和适度的睡眠模式可能有助于减轻轻度炎症.
- 需要进一步的研究来确认因果关系和探索干预措施.
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