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Updated: Jan 10, 2026

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线粒体表观遗传重塑和微囊素-LR诱导的综合应激反应:实验证据和初步的PP2A结构向

Nikita Soni1, Apoorva Chouksey1, Vikas Gurjar2

  • 1Division of Environmental Biotechnology, Genetics & Molecular Biology (EBGMB), ICMR-National Institute for Research in Environmental Health (NIREH), Bhopal, India.

Toxicon : official journal of the International Society on Toxinology
|November 27, 2025
PubMed
概括

微囊素-LR (MC-LR) 暴露会破坏线粒体功能并改变表观遗传调节,包括DNA和RNA甲基化. 分子对接表明蛋白酸酶2A (PP2A) 是一个潜在的MC-LR目标,影响细胞健康.

关键词:
环境毒理学环境毒理学表观遗传修饰 表观遗传修饰 表观遗传修饰在MC-LR中,它是最重要的.线粒体中毒性 线粒体中毒性分子对接是分子对接.

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