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Updated: Jan 10, 2026

X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050
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X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050

Published on: May 13, 2020

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对古代dUTPase的结构和功能洞察力揭示了一个子域介导的基质识别和进化适应机制

Sheng-Chia Chen1, Chun-Chi Chou2, Wen-Ming Chen1

  • 1Department of Seafood Science, National Kaohsiung University of Science and Technology, Kaohsiung 81157, Taiwan.

International journal of biological macromolecules
|November 27, 2025
PubMed
概括

考古时代的dUTPases对于核酸代谢至关重要,但人们对其了解甚少. 这项研究揭示了Methanosarcina mazei dUTPase的一个独特的结构机制,扩大了对酶多样性的知识.

关键词:
晶体结构 晶体结构进化上的分歧.结构性插入 结构性插入三元酶酶是三元酶中的一种.在 dUTPase 中.

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