相关实验视频
Updated: Jan 10, 2026

04:41
Measuring Lactase Enzymatic Activity in the Teaching Lab
Published on: August 6, 2018
116.4K
成年人乳糖呼吸试验:这些症状是否预示着乳糖吸收不良?
Davide G Cassella1, Nunzio Zignani1, Carolina Cavazzuti1
1Gastroenterology Unit, Department of Biomedical and Clinical Sciences, "L. Sacco" Hospital, University of Milan, Milan, Italy.
Clinical nutrition ESPEN
|November 27, 2025
概括
在乳糖气呼吸测试 (HBT) 期间症状的严重程度可以预测乳糖吸收不良 (LM). 浮是关键指标,甲测量可以改善诊断,以更好地管理乳糖不耐受 (LI).
科学领域:
- 胃肠病学 胃肠病学
- 消化系统健康 消化系统健康
- 诊断医学 诊断医学
背景情况:
- 乳糖不良吸收 (LM) 很普遍,但并非所有LM患者都会出现乳糖不耐受 (LI) 的症状.
- 在气呼吸测试 (HBT) 期间评估症状的诊断实用性,以预测LM需要进一步调查.
- 甲 (CH4) 测量在提高LM的HBT诊断准确性的作用尚未完全确定.
研究的目的:
- 评估HBT期间记录的症状是否可以预测LM.
- 为了确定CH4测量是否为识别LM提供了额外的诊断价值.
- 为了将症状严重程度与LM和HBT结果相关联.
主要方法:
- 对199名接受标准化乳糖HBT的成年人进行了回顾性分析.
- 症状分级使用数值评分尺度 (NRS) 对测试前和测试中的症状进行分级.
- 由H2升高 (≥20 ppm) 定义的LM;由CH4升高 (≥10 ppm) 定义的CH4阳性;进行统计分析.
主要成果:
- 在56.8%的参与者中检测到LM;84.9%在测试期间报告了症状.
- 在HBT期间的浮与LM (p < 0.01) 和峰值H2值密切相关.
- 严重的症状 (NRS ≥6) 与较高的LM患病率 (39.8%与18.6%相比;p < 0.01) 有关.
- CH4阳性发生在19.1%的病例中;LM仅在3.5%的病例中被CH4确定.
结论:
- 在HBT期间标准化的症状记录,特别是浮气,在临床上是有用的,用于识别功能性胃肠道症状的成年人中的LM.
- 症状严重程度分级有助于区分吸收不良并可以指导有针对性的管理.
- 将CH4测量与H2相结合,有可能提高LM的诊断准确性.
相关概念视频
Serum Laboratory Studies, Stool Test, Breath Test
730
Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
730
Assessment of the Gastrointestinal System I: Subjective Data
596
Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems...
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems...
596
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
617
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
617
Diabetes: Symptoms, Diagnosis, and Complications
2.0K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.0K
Glucose Transporters
27.1K
Glucose transporters facilitate the transport of glucose across the cell membrane. In addition to glucose, some glucose transporters can also aid the movement of other hexoses such as fructose, mannose, and galactose.
Facilitated diffusion-glucose transporters (GLUTs) are encoded by the solute-linked carrier (SLC) family 2, subfamily A gene family, or SLC2A. The 14 GLUT protein members are distributed into three classes:
Facilitated diffusion-glucose transporters (GLUTs) are encoded by the solute-linked carrier (SLC) family 2, subfamily A gene family, or SLC2A. The 14 GLUT protein members are distributed into three classes:
27.1K
Pulmonary Tuberculosis IV
468
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
468

![Assessment of Gastric Emptying in Non-obese Diabetic Mice Using a [13C]-octanoic Acid Breath Test](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F50301.jpg&w=3840&q=50)