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18

在癌症中解开p53错误折叠的陪伴者

Nusrat Jan1, Asma Jan1, Shazia Sofi1

  • 1Cancer Biology Laboratory, Department of Bioresources, School of Biological Sciences, University of Kashmir, Srinagar, J&K, India.

Advances in protein chemistry and structural biology
|November 27, 2025
PubMed
概括

癌细胞通常具有错误的p53通路,导致蛋白质错误折叠和聚合. 这项研究探讨了热冲击蛋白 (HSP),特别是HSP40/JDPs如何与p53相互作用,以推进癌症治疗策略.

关键词:
癌症 癌症 癌症 癌症陪伴者 (Chaperons) 是指一个陪伴者.热冲击蛋白质是一种热冲击蛋白质.错误折叠 没有错误折叠突变的p53是一种突变.突变 突变 突变 突变 突变野生类型的p53

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