年龄分层的并发症转变和9种过敏疾病的相互联系的映射
Ju Hee Kim1, Eun Lee2, Jeewon Shin3
1Department of Pediatrics, College of Medicine, Kyung Hee University Medical Center, Kyung Hee University, Seoul, South Korea.
过敏性疾病的患病率和多病症在各个年龄段都在增加,慢性疹,亚托皮炎和喘等疾病之间存在显著联系. 为了更好的管理,需要综合,生命周期战略.
科学领域:
- 免疫学和公共卫生
- 慢性病的流行病学 慢性病的流行病学
背景情况:
- 过敏性疾病很常见,慢性炎症状况通常与共享的免疫路径有关.
- 有限的人口层面的数据存在于过敏性疾病的趋势在整个寿命和他们的多病态模式.
研究的目的:
- 调查9种过敏疾病的特定年龄的流行趋势.
- 为了分析过敏疾病的模式,多病症.
- 在全国范围的队列中检查过敏状况之间的纵向相互关系.
主要方法:
- 利用了来自1,137,861个人的数据 (韩国国家医疗保险服务-全国样本队列,2002-2019).
- 追踪了九种过敏性疾病:阿托皮性皮肤炎,喘,过敏性鼻炎,食物过敏,药物过敏,过敏性过敏,过敏性结膜炎,急性和慢性.
- 评估了使用有条件的考克斯模型和网络图的流行率,并发病率和疾病之间的关联.
主要成果:
- 大多数过敏性疾病的患病率在所有年龄组都增加,包括儿童和老年人.
- 患有两种或两种以上过敏症的个体比例从0.7%上升到4.2%.
- 慢性疹,亚托皮炎和喘被确定为其他过敏疾病的关键前体;关联因年龄而异,在成年时更强烈.
结论:
- 过敏性疾病在一生中呈现出越来越多的患病率和多病率,与年龄相关的相互关系.
- 这些发现强调了对过敏性疾病监测和管理的综合性,终身方法的必要性.
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