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Updated: Jan 10, 2026

A Method for Screening and Validation of Resistant Mutations Against Kinase Inhibitors
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准KRAS突变:编排癌症演变和治疗挑战

Khalil Choucair1, Hafsa Imtiaz1, Md Hafiz Uddin1

  • 1Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA.

Signal transduction and targeted therapy
|November 27, 2025
PubMed
概括

针对癌症中的KRAS突变显示出希望,但目前对KRAS G12C的治疗方法的疗效和耐药性有限. 新的策略正在探索各种KRAS突变的组合疗法,包括胰腺癌.

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