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开发一种丰富的酵母菌株,用于营养应用,使用低成本的原料

Pegah Zare¹, Minoo Giyahchi¹, Tabasom Entezari¹

¹Department of Microbiology, School of Biology, College of Science, University of Tehran, Tehran, Iran.

Scientific reports

|November 27, 2025

概括

这项研究优化了Candida sp.中的丰富. pz46酵母,在具有成本效益的基板上实现高生物质产量. 由此产生的富含的酵母生物质是无毒的,有效释放,提供了对抗缺乏症的策略.

科学领域:

生物技术是生物技术.
营养科学营养科学
微生物学微生物学

背景情况:

缺乏是全球重要的健康问题,影响着许多身体功能.
开发高效和可持续的生物强化方法至关重要.

研究的目的:

为了隔离和表征一种酵母菌株的高积累.
优化选定酵母菌株的生物质生产,使用具有成本效益的基板.
评估丰富酵母作为营养补充剂的潜力.

主要方法:

对50种酵母分离物的查,以检测的耐受性和积累.
使用响应表面方法 (Box-Behnken设计) 优化生物质产量,使用甘糖蜜和玉米酒.
对积累与Saccharomyces cerevisiae的比较分析.
在体外消化和细胞毒性 (MTT测定) 试验.

主要成果:

在Candida sp.中. pz46表现出高耐受性 (1 g/L) 和积累了约700毫克Zn/g干生物质.
在优化条件下,使用甘糖蜜和玉米酒的生物质产生了14.49g/L.
在Candida sp.中. 与Saccharomyces cerevisiae相比,pz46表现出更高的生长和积累.
在模拟消化过程中,超过77%的细胞内被释放出来,没有观察到细胞毒性.

结论:

在Candida sp.中. pz46是工业规模生产丰富酵母的有希望的候选者.
像甘糖蜜和CSL这样的可持续基质对于生物质生产是有效的.
丰富的酵母生物质提供了安全和生物可用的来源,以应对缺陷.

关键词:

生物吸收生物吸收玉米的烈酒,的酒.丰富的酵母是一种丰富的酵母.细胞内积累的细胞内积累.糖蜜糖是什么意思糖蜜糖是什么意思营养补充剂营养补充剂

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