在伊朗建立一个国家儿科干细胞移植注册表,以应对实施和数据质量方面的挑战
Bibi Shahin Shamsian1, Nader Momtazmanesh1, Vahide Zeinali2
1Pediatric Congenital Hematologic Disorders Research Center, Research Institute for Children's Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Scientific reports
|November 27, 2025
概括
建立伊朗儿科造血干细胞移植注册表 (IPED-HSCT) 证明是可行的,数据完整性超过90%. 这个倡议为发展中国家的儿科干细胞移植注册表提供了一个可扩展的模型.
科学领域:
- 儿科血液学 儿科血液学
- 干细胞移植 干细胞移植
- 医疗信息学 医疗信息学
背景情况:
- 儿科造血干细胞移植 (HSCT) 需要强大的数据收集以进行研究和改善结果.
- 伊朗儿科造血干细胞移植注册表 (IPED-HSCT) 是为了满足这一需求而启动的.
- 标准化注册表对于推进儿科HSCT护理至关重要.
研究的目的:
- 评估实施标准化儿科HSCT注册表的可行性和可靠性.
- 评估IPED-HSCT注册表中的数据完整性和用户满意度.
- 探索IPED-HSCT注册表作为资源有限设置模型的潜力.
主要方法:
- 在伊朗的三个儿科HSCT中心使用了基于社区的参与方法.
- 多阶段的注册表开发包括试点测试和基于Web的系统实施.
- 来自50名儿科HSCT患者 (恶性和非恶性疾病) 的数据使用SPSS收集和分析.
主要成果:
- IPED-HSCT注册表实现了超过90%的数据完整性.
- 在平台设计和培训方面,用户满意度很高.
- 参与者的人口统计包括62%的男性和38%的女性.
结论:
- 一个强大的儿科HSCT注册表是可行的,即使在资源有限的环境中.
- IPED-HSCT注册表为全球类似举措提供了一个可扩展的模型.
- 未来的努力应优先考虑长期的可持续性和国际合作,以提高儿科HSCT的结果.
相关概念视频
Stem Cell Therapy for Tissue Regeneration
4.6K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.6K
iPS Cell Differentiation
3.0K
The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
3.0K
Tissue Transplantation
870
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
870
Bone Marrow Sampling and Transplants
829
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
829
Regulation of Hematopoietic Stem Cells
3.9K
All blood and immune cells are produced from the multipotent hematopoietic stem cells (HSCs) by the process of hematopoiesis. However, they all have a limited life span. In addition, many are depleted in immune surveillance or combatting an injury or infection. This makes blood one of the most regenerative tissues. Hematopoiesis helps replenish these blood and immune cells, restoring the body's normal functioning. However, overproduction of blood and immune cells can make them cancerous or...
3.9K


