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Updated: Jul 7, 2026

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使用分子对接和动态学,在体内识别新型Cis-aconitate脱碳酶抑制剂作为潜在的抗炎药物

Mohammad Darvish Khadem1, Saeed Pirmoradi2, Mohammad Reza Tabandeh3,4

  • 1Department of Basic Sciences, Division of Biochemistry and Molecular Biology, Faculty of Veterinary Medicine, University of Semnan, Semnan, Iran.

Scientific reports
|November 27, 2025
PubMed
概括

研究人员确定了cis-aconitate脱碳酶 (CAD) 的新型抑制剂,这是炎症中至关重要的酶. 这些潜在的抗炎药物显示出有希望的结合性,稳定性和类似药物的特性,可用于未来的开发.

关键词:
在Cis-aconitate脱碳酶中.免疫反应基因1 免疫反应基因1抑制剂的抑制剂分子对接是分子对接.分子动力学分子动力学

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