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Updated: Jan 10, 2026

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation
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Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation

Published on: August 1, 2018

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富含二硫化物多硫类化合物通过电子二元性和形状响应识别来向血管内皮生长因子A

Biswajit Mohanty1, Parthapratim Munshi2

  • 1Multifunctional Molecular Materials Laboratory, Department of Chemistry, School of Natural Sciences, Shiv Nadar Institution of Eminence Deemed to be University, Delhi-NCR, Uttar Pradesh, 201314, India.

Scientific reports
|November 27, 2025
PubMed
概括

研究人员发现了新的小分子,lyssoclibadins (LCs),有效抑制血管内皮生长因子A (VEGFA). 这些化合物向以前"不可抗药"的蛋白质接口,为血管生成驱动的疾病提供新的治疗策略.

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