蓝藻细菌中多细胞性基因的演变导致了大氧化事件
Joanne S Boden1,2, Mercedes Nieves-Morión3, Dennis Nürnberg4
1School of Geographical Sciences, University of Bristol, Bristol, United Kingdom.
Communications biology
|November 27, 2025
概括
阐述了蓝藻细菌多细胞性的演变,这是大氧化事件 (GOE) 的关键. 细胞结合和分化的基因在27亿年前出现,使早期的复杂生命成为可能.
科学领域:
- 进化生物学是进化的生物学.
- 原生生物的多样性
- 生物地质化学生物地质化学
背景情况:
- 菌是关键的原生细胞,驱动了对复杂生命至关重要的大氧化事件 (GOE).
- 它们表现出不同的形态,从单细胞到多细胞的纤维,具有细胞分化.
- 丝状蓝藻细菌背后的进化机制仍然不太清楚.
研究的目的:
- 确定参与蓝藻细菌多细胞性和细胞分化的基因的进化时间表.
- 为了研究早期分支的丝状蓝藻细菌的功能能力.
主要方法:
- 人类基因组学分析
- 贝叶斯分子时钟的约会时间
- 基因树物种树的和解 基因树物种树的和解
- 隔膜结构的表征
- 测量细胞间的分子转移.
主要成果:
- 隔膜蛋白 (sepJ,sepI) 和分化调节器 (hetR) 的基因在26~27亿年前 (Ga) 进化.
- 差异化基因 (hetZ,patU3) 和隔膜复杂性 (hglK) 出现了大约2.5亿年前,与GOE相吻合.
- 细胞间分子交换证实在多种细丝状蓝藻细菌中,包括早期分支的Pseudanabaena.
结论:
- 蓝藻细菌的多细胞化和分化的遗传工具包早于GOE.
- 早期的丝状蓝藻细菌拥有细胞间通信能力,这对于它们的生态作用至关重要.
- 这项研究为地球上复杂生命的进化起源提供了洞察力.
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