相关实验视频

Updated: Jan 10, 2026

Strand-Specific Analysis of Proteins at Replicating DNA Strands by Enrichment and Sequencing of Protein-Associated Nascent DNA Method
08:53

Strand-Specific Analysis of Proteins at Replicating DNA Strands by Enrichment and Sequencing of Protein-Associated Nascent DNA Method

Published on: May 2, 2025

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以AlphaFold为指导的遗传学分析表明,甲动物复制起源许可机制中的异质性令人惊

Olivia Hunker1, Franziska Bleichert2

  • 1Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.

The EMBO journal
|November 27, 2025
PubMed
概括

DNA复制需要准确的原产地许可. 研究人员发现,蛋白质子单元 (ORC6) 并非总是为载入MCM基酶而必不可少的,揭示了在许多动物物种中保存的另一个ORC6-独立机制.

关键词:
阿尔法折叠是什么意思阿尔法折叠DNA复制启动 DNA复制启动原产地许可证的授权结构遗传学 结构遗传学

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