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Updated: Jan 10, 2026

High-throughput Antiviral Assays to Screen for Inhibitors of Zika Virus Replication
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High-throughput Antiviral Assays to Screen for Inhibitors of Zika Virus Replication

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高通量体外查和in silico分析用于寨卡病毒抑制剂识别

Sania Batool1, Santosh Chokkakula1, Beom Kyu Kim1,2

  • 1Department of Microbiology, Chungbuk National University College of Medicine and Medical Research Institute, Cheongju, Chungbuk, 28644, Republic of Korea.

Scientific reports
|November 27, 2025
PubMed
概括

研究人员选了348种化合物以寻找寨卡病毒 (ZIKV) 治疗方法,确定了7种有效的抗病毒候选物. 赛可沙尼B2和塞法洛素显示出对ZIKV药物开发的前景,尽管存在一些化合物限制.

关键词:
在ADMET分析中,分析了ADMET.抗病毒查 抗病毒查分子对接是分子对接.寨卡病毒 寨卡病毒

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Genetic Screens02:46

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
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