丸激素和下尿道症状:叙述性审查
Colin J O'Mahony1,2, M A Arshad3, S M Norton3,4
1Department of Urology, University Hospital Limerick, Dooradoyle, Limerick, Ireland. colinjomahony@gmail.com.
Current urology reports
|November 27, 2025
概括
低水平可以通过炎症和代谢问题加剧下尿道症状 (LUTS). 当监测时,生理丸激素治疗对LUTS是安全的,改善了泌尿功能和生活质量.
科学领域:
- 内分泌学 在内分泌学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 代谢健康 代谢健康
背景情况:
- 在男性中,下泌尿道症状 (LUTS) 是常见的.
- 在LUTS中的作用是复杂的,涉及内分泌,代谢和炎症途径.
- 现有证据表明,丸激素会影响膀,前列腺和骨盆底功能.
研究的目的:
- 审查目前关于男性丸激素和LUTS之间的关系的证据.
- 探索涉及的内分泌,代谢和炎症机制.
- 讨论对临床实践和患者管理的影响.
主要方法:
- 对最近的实验和临床研究进行系统审查.
- 对雄激素受体通路及其对下泌尿道组织的影响的分析.
- 对丸激素缺乏和治疗对LUTS和前列腺结局的影响的评估.
主要成果:
- 缺乏会放大炎症,氧化应激和血管功能障碍,导致LUTS.
- 代谢综合征,阴性双胞胎症和睡眠障碍加剧了LUTS的严重程度.
- 生理丸激素治疗,当适当监测时,不会使LUTS或前列腺结果恶化.
- 缺乏症通过全身机制导致LUTS,而不仅仅是解剖学的机制.
结论:
- 恢复生理丸激素平衡,解决代谢和睡眠因素,可以改善LUTS男性的泌尿功能和生活质量.
- 未来的研究应该专注于表型特异性试验和针对个性化护理的综合代谢内分泌泌泌尿学方法.
- 丸激素治疗可以是一个安全和有效的组成部分,在低腺男性的LUTS管理.
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