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Updated: Jan 6, 2026

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优化共表达策略,在CHO细胞中同时显示和分泌单克隆抗体

Jessica P Z Ng1, Mariati Mariati1, Han Kee Ong1

  • 1Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01 Centros, Singapore, 138668, Singapore.

Scientific reports
|November 27, 2025
PubMed
概括

优化哺乳动物细胞载体设计对于抗体工程至关重要. 在双显示和分泌 (dualDS) 系统中,Fm-2A系统展示了优越的抗体显示和分泌效率.

关键词:
在CHO细胞中.共同表达是一种共同表达.双显示和分泌的双显示.毛皮的裂变 毛皮的裂变单克隆抗体是一种单克隆抗体.矢量设计 矢量设计

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