饮食中的抗氧化剂和CKM-抑郁症共患病症:使用六种机器学习算法对所有原因死亡率进行初级分析和二次评估
Yi Tang1,2, Zilong Yue3, Juncang Wu1,2
1Department of Neurology, Anhui Medical University, Hefei, 230032, China.
European journal of medical research
|November 28, 2025
概括
饮食中摄入特定的安托西亚尼丁,如尼丁和尼丁,与降低伴随性抑郁症和心血管疾病的几率有关. 更高的摄入量也与美国成年人全因死亡风险较低有关.
科学领域:
- 营养流行病学 营养流行病学
- 心血管健康 心血管健康
- 心理健康研究 心理健康研究
背景情况:
- 调查饮食中抗氧化剂与并发性疾病之间的联系.
- 检查与心血管精神健康 (CKM) 的关联,抑郁症并发症和全因死亡率.
研究的目的:
- 为了确定饮食中抗氧化剂的摄入是否与CKM-抑郁症并发症相关.
- 评估饮食中抗氧化剂与美国成年人全因死亡率之间的关联.
主要方法:
- 对2007-2010年NHANES数据的观察分析与相关的死亡率.
- 利用机器学习 (LASSO,Boruta,LGBM) 进行预测器选择和分类.
- 使用多变量逻辑回归和Cox比例危险模型进行关联分析.
主要成果:
- 摄入较高的尼丁,尼丁和总安托西亚尼丁与较低的CKM-抑郁症并发症几率有关.
- 佩图尼丁和安东基亚尼丁总摄入量与降低全因死亡风险有关.
- 机器学习模型,特别是LGBM,在预测方面表现出很高的表现.
结论:
- 特定的安托西亚尼丁与较低的CKM-抑郁症共发病率呈现横截面关联.
- 佩图尼丁和总安托西亚尼丁与降低死亡风险有关.
- 结果表明潜在的好处,但由于观察设计,需要谨慎解释.
相关概念视频
Chronic Kidney Disease III: Interprofessional Care
323
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
323
Coronary Artery Disease I: Introduction
850
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
850
Chronic Kidney Disease IV: Nursing Management
299
Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
299


