相关实验视频

Updated: Jul 11, 2026

Rapid Fluorescence-based Characterization of Single Extracellular Vesicles in Human Blood with Nanoparticle-tracking Analysis
09:16

Rapid Fluorescence-based Characterization of Single Extracellular Vesicles in Human Blood with Nanoparticle-tracking Analysis

Published on: January 7, 2019

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通过单分子检测利用直接随机光学重建显微镜在细胞外囊中的蛋白质素化进行剖析

Sarah R Needham1, Benjamin M Davis1, Pinar Uysal-Onganer2

  • 1Central Laser Facility, UKRI: Science & Technology Facilities Council, Rutherford Appleton Laboratory, Oxfordshire, UK.

Journal of biophotonics
|November 28, 2025
PubMed
概括

这项研究揭示了在细胞外囊泡 (EV) 的内部和表面都存在素蛋白质. 这些发现提升了在癌症诊断液体活检中使用EV素形状的潜力.

关键词:
贝叶斯模型是贝叶斯模型.素基因组 H3 的素基因组 H3 的素基因组引流化/减轻化的情况dSTORM 这是一个风暴.细胞外囊泡中的细胞外囊泡.液体活检活检液体活检单个分子检测检测.

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Direct Stochastic Optical Reconstruction Microscopy of Extracellular Vesicles in Three Dimensions

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Multimodal Analytical Platform on a Multiplexed Surface Plasmon Resonance Imaging Chip for the Analysis of Extracellular Vesicle Subsets06:12

Multimodal Analytical Platform on a Multiplexed Surface Plasmon Resonance Imaging Chip for the Analysis of Extracellular Vesicle Subsets

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相关概念视频

Immunogold Electron Microscopy01:20

Immunogold Electron Microscopy

Immunoelectron microscopy utilizes immunogold labeling of endogenous proteins with specific antibodies to detect and localize these proteins in cells and tissues. The procedure provides insights into the distribution and quantification of protein under different stimulation conditions offering clues about their functions. Conjugating highly electron-dense gold particles with primary or secondary antibodies allow antigen detection on and within cells, with high resolution and specificity.
Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...