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调节突巨对 nociceptive 信号的反应减轻了类风湿性关节炎的炎症

Lan Lin1, Yang Chen1, Yiming Lin1

  • 1Department of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou 350212, China; Department of Orthopedic Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China; Fujian Provincial Institute of Orthopedics, the First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, China.

Molecular therapy : the journal of the American Society of Gene Therapy
|November 28, 2025
PubMed
概括

在类风湿性关节炎 (RA) 中,由免疫复合体激活的可感应神经释放素基因相关 (CGRP),以减少炎症. 然而,长时间的激活会使巨细胞变得不敏感,因此需要使用诸如CGRP受体过度表达等治疗策略.

关键词:
这是CGRP的CGRP.免疫力是一种免疫力.感觉神经是一种感觉神经.类风湿性关节炎 类风湿性关节炎突细胞的巨细胞.

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