卡塔托尼亚是神经精神病性狼的初始表现
Abihai Lucas-Hernández1, Blanca Estela Hernández-Sánchez2, Alexis Rojas-Xicohténcatl2
1Rheumatology department, Hospital General de Teziutlán, IMSS-BIENESTAR. Calle Bugambilias #7, Teziutlán, Puebla 73960, México.
Oxford medical case reports
|November 28, 2025
概括
触角炎可能是系统性红斑狼 (SLE) 的第一个迹象,这是一个罕见的自身免疫性疾病. 早期诊断和治疗,包括对抗核糖体P抗体的监测,对于恢复至关重要.
科学领域:
- 神经精神病学是一种神经精神病学.
- 类风湿病学 类风湿病学
- 免疫学 免疫学 免疫学
背景情况:
- 卡塔托尼亚是一种罕见的神经精神综合征.
- 系统性红斑狼 (SLE) 是一种具有多种表现的自身免疫性疾病.
- 作为SLE的初始表现形式的卡塔托尼异常罕见.
研究的目的:
- 报告一例catatonia作为SLE的初始表现.
- 突出抗核体P抗体在神经精神病性SLE的诊断意义.
- 强调在新发性SLE的差异诊断中考虑catatonia的重要性.
主要方法:
- 一个32岁妇女的病例报告.
- 临床表现:严重的白内障,自身免疫性血液溶解性贫血,狼性肝炎.
- 诊断工作包括ANA,抗SM,抗核体P,抗dsDNA,补充水平和SLEDAI-2K得分.
- 治疗包括高剂量的皮质类固醇,环胺,氧化和洛拉泽.
主要成果:
- 这位患者呈现出白内障,这是SLE的第一个迹象.
- 满足了SLE的诊断标准,得到了积极的自身抗体 (ANA,抗SM,抗核体P,抗dsDNA) 和低补充的支持.
- 抗脂抗体是负的.
- 患者在三天内明显改善,在两周内完全康复,并没有复发.
结论:
- 卡塔托尼亚可能是神经精神病性SLE的初始表现.
- 在这种情况下,抗核体P抗体是重要的诊断标记物.
- 及时诊断和积极的免疫抑制疗法导致了与SLE相关的catatonia的良好结果.
相关概念视频
Positive Symptoms of Schizophrenia: Hallucinations and Delusions
510
Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
510
Parkinson's Disease: Overview
1.7K
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
1.7K
Chronic Kidney Disease II: Clinical Manifestations
529
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
529
Narcolepsy
466
Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
466
Psychosis: Goals of Pharmacotherapy
446
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
446
Mania and Antimanic Drugs: Overview
530
Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as...
530


