短链脂肪酸和2型糖尿病:对知识结构,研究热点和未来方向的文献统计分析
Likun Zheng1, Rongsheng Jiang1, Jinxu Fang1
1College of Acupuncture and Tuina, Changchun University of Chinese Medicine, Changchun, China.
Frontiers in microbiology
|November 28, 2025
概括
短链脂肪酸 (SCFA) 与2型糖尿病 (T2DM) 有关. 研究突出了肠道微生物群,代谢学和饮食干预措施,为个性化营养和微生物疗法铺平了道路.
科学领域:
- 内分泌学和新陈代谢学
- 微生物学 微生物学
- 营养科学 营养科学
背景情况:
- 2型糖尿病 (T2DM) 是一个重大的全球健康挑战.
- 由肠道微生物群产生的短链脂肪酸 (SCFA) 越来越多地被认为是T2DM病原体中的作用.
- 了解SCFA和T2DM之间的关系对于开发新的治疗策略至关重要.
研究的目的:
- 系统地绘制SCFA和T2DM研究的知识结构.
- 确定当前的研究热点和该领域的新兴趋势.
- 概述未来的研究方向,以了解T2DM中的SCFA机制.
主要方法:
- 对Scopus和Web of Science的965篇出版物进行了图书统计和视觉分析.
- 使用VOSviewer和CiteSpace进行数据可视化和分析.
- 关键词分析以确定核心研究主题和有影响力的术语.
主要成果:
- 自2016年以来,人们观察到出版物的快速增长,这表明研究兴趣日益增加.
- 中国在出版量方面处于领先地位; 美国在合作和影响力方面处于中心地位.
- 关键的研究术语包括"肠道微生物群"",代谢学"",微生物代谢"",胰岛素耐药性"和"饮食干预".
结论:
- 目前的研究重点是阐明SCFA在T2DM中的作用和机制,向临床应用过渡.
- 临床策略正在从一般的饮食建议演变为精确的营养配方.
- 代谢学方面的进步将大大支持该领域的基础和临床研究.
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