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试验研究的泰TM单枢纽专利孔圆形封闭器

Kun Wang¹, Xian-Zi Zeng^1,2, Zhen-Wei Liang^1,2

¹Zhuhai People's Hospital, Zhuhai Clinical Medical College of Jinan University, Zhuhai.

Acta Cardiologica Sinica

|November 28, 2025

概括

在TAI QINGTM单枢纽封闭器证明了安全性和有效性在狗的临床前专利卵孔 (PFO) 关闭. 这种设备对未来的人类临床试验充满希望.

科学领域:

心血管研究研究心血管研究
医疗设备创新医疗设备创新
临床前研究临床前研究

背景情况:

圆孔 (PFO) 是一种常见的心脏异常.
过导管装置的关闭是PFO手术的替代方案.

研究的目的:

评估TAI QINGTM PFO关闭单枢纽封闭器的可行性,安全性和有效性.
评估设备在临床前动物模型中的性能.

主要方法:

十二只拉布拉多犬在光学指导下进行了PFO创建和随后的装置植入.
动物在1,3,9和12个月时被牺牲,用于宏观和组织学评估.

主要成果:

在100%的受试者中成功植入了TAI QINGTM封闭器,没有任何术前并发症.
观察到装置稳定性和组织整合,内皮质化和原沉积在12个月后明显.
在研究期间没有报告与植入物相关的不良事件.

结论:

在临床前的犬类模型中,TAI QINGTM单枢纽封闭器对PFO关闭是安全有效的.
结果支持在更大的动物研究和人类临床试验中进一步调查.

关键词:

这是一个 Occluder 封闭器.专利对于形形的人.单个枢纽的单个枢纽.太极拳TM 太极拳TM

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