使用实时可穿戴设备和智能手机应用程序对功能性消化不良患者自主功能进行分析
Fumio Tanaka1, Rieko Nakata1, Noriaki Sugawara2
1Department of Gastroenterology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan.
Journal of clinical biochemistry and nutrition
|November 28, 2025
概括
功能性消化不良 (FD) 患者表现出异常的自主神经系统 (ANS) 活动,与症状和生活质量下降有关. 这项研究揭示了FD的症状期间的副交感神经系统功能障碍.
科学领域:
- 胃肠病学 胃肠病学
- 神经科学是一个神经科学.
- 生理学 生理学 生理学
背景情况:
- 自主功能障碍与功能性消化不良 (FD) 有关,但其具体机制尚不清楚.
- 了解自主神经系统 (ANS) 活动,生活事件和胃肠道症状之间的相互作用对于FD管理至关重要.
研究的目的:
- 通过实时监测,阐明FD患者的ANS活动,生活事件和腹部症状之间的关系.
- 在FD的症状期内调查ANS活动模式,特别是交感和副交感神经功能.
主要方法:
- 展望性,多中心研究涉及9名FD患者和23名健康对照 (HC).
- 使用可穿戴的T恤设备进行24小时连续的ANS活动监控.
- 通过智能手机应用程序同时记录生活事件和腹部症状.
主要成果:
- 与HC相比,FD患者的异常低频/高频 (LF/HF) 和高频 (HF) 信号数量显著增加.
- 异常的ANS信号与腹症状严重程度正相关,与生活质量 (QOL) 负相关.
- 在症状期间,HC患者显示HF升高,而FD患者显示HF降低,这表明了副交感功能障碍.
结论:
- FD的特点是异常的ANS活动,与症状负担和降低QOL相关.
- 有证据表明,副交感神经系统功能障碍是FD症状发作期间的关键特征.
- 实时监测为ANS在功能性消化不良的病理生理学中的作用提供了宝贵的见解.
相关概念视频
01:30Pulse rhythm
1.3K
Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
1.3K
01:23Holter Monitor: 24-Hour Monitoring
1.9K
Holter monitoring is a continuous electrocardiography (ECG) recording that tracks the heart's electrical activity over an extended period, generally 24 to 48 hours. This noninvasive diagnostic tool detects irregular heart rhythms that may not be captured during a standard ECG performed in a clinical setting.DeviceThe Holter monitor is a portable, small device connected to several electrodes on the patient's chest. These electrodes detect the heart's electrical signals and transmit them to the...
1.9K
01:29Assessment of the Gastrointestinal System II: Health Perception Pattern
434
Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
434