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Updated: Jan 10, 2026

Determination of the Transport Rate of Xenobiotics and Nanomaterials Across the Placenta using the ex vivo Human Placental Perfusion Model
08:08

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Published on: June 18, 2013

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在怀孕期间优化venlafaxine治疗:一种母胎PBPK建模方法

Seo-Yeon Choi1, Eunsol Yang2, Kwang-Hee Shin1,3

  • 1College of Pharmacy, Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, Republic of Korea.

Drug design, development and therapy
|November 28, 2025
PubMed
概括

一个新的基于生理学的药理动力学模型有助于优化怀孕期间的拉法辛剂量. 建议每天服用150毫克剂量,以平衡孕产妇和胎儿的安全性和疗效.

关键词:
在O-desmethylvenlafaxine的使用中.在 PBPK 建模中使用 PBPK 模型.怀孕 怀孕 怀孕 怀孕 怀孕维纳拉法辛 (venlafaxine) 是一种药物.

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