在接受脊髓炎治疗的儿童中,基于nomogram的持续轴延长的预测
Xiangxiang Fu1, Quanyong Yi2, XiaoLi Mao1
1Yuyao Maternity and Child Health Care Hospital (Yuyao Second People's Hospital), Ningbo, China.
Frontiers in medicine
|November 28, 2025
概括
一个新的预测模型有助于个性化近视控制,用于使用正视眼镜 (OK) 镜头的儿童. 这种工具有助于分层风险,以便在儿科近视管理中获得更好的治疗结果.
科学领域:
- 眼科医生 眼科 眼科
- 儿科光学测量 儿科光学测量
- 近视控制研究近视研究
背景情况:
- 近视是一个重要的全球健康问题,特别是在儿童中.
- 整形眼镜 (OK) 镜头为近视控制提供了有希望的结果.
- 在OK治疗结果的个体变化需要个性化的方法.
研究的目的:
- 开发和验证一个预测模型,对近视儿童的Orthokeratology治疗结果进行预测.
- 确定影响近视控制成功的关键预测因子,使用OK镜头进行近视控制.
- 创建一个工具,用于儿童近视管理的个体风险预测.
主要方法:
- 对接受OK治疗的439名近视患者进行了回顾性队列研究.
- 使用后勤回归和最小绝对收缩和选择运算符 (LASSO) 回归的预测模型的开发.
- 使用校准图,ROC曲线和决策曲线分析 (DCA) 验证模型.
主要成果:
- 开发了一个结合年龄,父母近视,白色到白色距离和球形折射的预测模型.
- 该模型显示出强大的区分能力,AUC为0.831 (训练) 和0.820 (测试).
- 观察到高灵敏度和特异性,证实了该模型的临床实用性.
结论:
- 成功开发了一种有效的预测模型,用于在儿科近视症中获得正视结局的正视结局.
- 该模型有助于对个性化近视管理的风险分层.
- 为临床实施,建议在不同人群中进行进一步的前性验证.
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