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Updated: Jan 10, 2026

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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新型pyrazole衍生物及其抗癌和CDK2抑制活性的环保合成

Samar A Abubshait1,2, Lamia H T Amin3, Abeer M El-Naggar4

  • 1Department of Chemistry, College of Science, Imam Abdulrahman Bin Faisal University P. O. Box 1982 Dammam 31441 Saudi Arabia sabubshait@iau.edu.sa.

RSC advances
|November 28, 2025
PubMed
概括

新的皮拉衍生物显示出强大的CDK2抑制和抗癌活性. 化合物5有效地抑制CDK2,并诱导癌细胞的亡,为药物开发提供了一个有希望的线索.

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