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Updated: Jun 16, 2026

Using Lipid Nanoparticles for the Delivery of Chemically Modified mRNA into Mammalian Cells
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Using Lipid Nanoparticles for the Delivery of Chemically Modified mRNA into Mammalian Cells

Published on: June 10, 2022

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经过甲基链修改的人工病毒体,用于增强mRNA的细胞内传递

Avijit Ghosh1, Yuka Yamamoto1, Mizuki Wada1

  • 1Department of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University, Tottori 680-8552, Japan.

Bioconjugate chemistry
|November 28, 2025
PubMed
概括

研究人员开发了一种新的基于的人工病毒囊,用于安全有效地输送信使RNA (mRNA) 疗法. 这种病毒模拟方法增强了细胞吸收和蛋白质表达,同时降低了细胞毒性,为基于核酸的药物提供了一个有希望的替代品.

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