糖尿病患者的自主神经病变
Lucianne Righeti Monteiro Tannus1, Roberta Arnoldi Cobas1
1Departamento de Clínica Médica, Unidade de Diabetes, Universidade Estadual do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.
糖尿病自主神经病变 (DAN) 是一种严重的糖尿病并发症,影响自主神经系统 (ANS). 这篇评论帮助临床医生识别和管理DAN.
科学领域:
- 内分泌学和新陈代谢学
- 神经学 神经学
- 心脏病学 心脏病学
背景情况:
- 糖尿病自主神经病变 (DAN) 是糖尿病的一种严重并发症.
- 它影响自主神经系统 (ANS) 的各个部分,导致各种症状.
- 心血管自主神经病变 (CAN) 是一种严重的形式,与死亡率的增加有关.
研究的目的:
- 为临床医生提供对DAN的实际理解.
- 帮助怀疑,调查和管理DAN.
- 专注于心血管 (CV),胃肠道 (GI) 和泌尿生殖系统 (GU) 的表现.
主要方法:
- 整合基础科学,流行病学和临床数据.
- 对病理生理学,临床表现和管理策略的审查.
- 专注于在临床实践中对DAN缺乏认可的方面.
主要成果:
- DAN涉及复杂的高血糖驱动路径,氧化应激和炎症.
- 症状不仅仅是心血管问题,还包括胃肠道,胃肠道和运动功能障碍.
- 由于亚临床发作和非特异性症状,DAN经常被忽视.
结论:
- DAN显著损害生活质量,并且往往没有得到充分的认可.
- 早期识别和管理对于患者的治疗结果至关重要.
- 本综述为临床医生提供了一份指南,以解决DAN的CV,GI和GU表现.
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