胃肠道内镜切除后患者报告的结果措施 (PROMs)
Laura Retzbach1, Karl-Hermann Fuchs1, Markus Brand1
1Department of Gastroenterology, Medizinische Klinik, University Hospital Würzburg, Würzburg, Germany.
United European gastroenterology journal
|November 28, 2025
概括
患者报告的结果测量 (PROM) 显著改善了内镜切除 (ER) 后的生活质量. 这种幸福感的增强源于胃肠道症状的减少和手术后的情绪困扰.
科学领域:
- 胃肠病学 胃肠病学
- 内視鏡外科手術 內視鏡外科手術
- 患者报告的结果
背景情况:
- 在内镜切除后,患者报告的结果测量 (PROM) 有有限的数据.
- 对患有胃肠粘膜瘤的患者来说,评估生活质量至关重要.
研究的目的:
- 在接受内镜切除 (ER) 的患者中前性评估胃肠道生活质量指数 (GIQLI).
- 测量生活质量的变化从基线到后ER对于上下胃肠道瘤.
主要方法:
- 有望的,单中心临床试验涉及238名患者.
- 利用36项GIQLI来评估症状,情绪状态和身体/社会功能.
- 在ER手术 (EMR,ESD,EFTR) 后收集了基线和4-6周的随访数据.
主要成果:
- 平均GIQLI得分从基线时的112.74显著增加到ER后的115.70 (p < 0.0001).
- 改善主要是由增强的情绪健康和更好的胃肠道症状得分所驱动的.
- 该研究分析了347名注册患者中的238名患者的数据,这些患者有ER的适应性.
结论:
- 内镜切除可以显著改善患者的生活质量.
- 减少症状和情绪负担有助于提高ER后的幸福感.
- 需要进一步的研究来探索特定内镜技术对患者结果的影响.
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