蛋白激酶抑制剂阿尔法通过cAMP-EPAC信号重编程驱动Ewing肉瘤中的温克里斯抗性

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Xin Zhou1,2, Yating Yu2, Hao Qiu1

  • 1Department of Orthopedic Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Molecular carcinogenesis
|November 28, 2025
PubMed
概括

蛋白激酶抑制剂α (PKIA) 通过重新编程cAMP-EPAC信号来驱动尤宁肉瘤中的化学抵抗. 通过EPAC抑制剂向这种途径,可以克服患者的耐药性.

关键词:
美国环保协会1 EPAC1尤文肉瘤 (Ewing Sarcoma) 是一种癌症.在PKIA中,PKIA是PKIA.在cAMP信号传输中.电阻的电阻是指电阻的电阻维克里斯蒂娜 维克里斯蒂娜

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