传染性发病率与在劳动诱导期间的早期胚胎切除相关
Corina N Schoen1, Elizabeth Baker2, Ravneet Thind2
1Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, UMASS Chan Medical School - Baystate, Springfield, MA 01199, USA.
在宫成熟开始后不到12小时进行羊膜切割并不会增加孕产妇或新生儿传染病发病率. 早期胚胎切除与减少传染性并发症,更短的分娩和更低的剖腹产率有关.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 生殖健康 生殖健康
背景情况:
- 宫成熟是劳动诱导中常见的一种干预.
- 在分娩诱导过程中人工膜破裂 (AROM) 的时间受到争议.
- 潜在的风险包括传染病发病率和长时间的分娩.
研究的目的:
- 调查早期羊膜切除与孕产妇/新生儿传染病发病率之间的关联.
- 为了比较早期胚胎切除 (成熟后<12小时) 与晚期胚胎切除的结果.
- 评估二次结果,如剖腹产和孕产妇发病率.
主要方法:
- 单中心回顾性队列研究 (2010-2018).
- 包括孕期妇女接受产业诱导与子宫成熟.
- 基于人工膜破裂 (AROM) 时间的结果进行比较.
主要成果:
- 感染性发病率 (胆 ?? 膜炎/新生儿败血症) 最低 (0.4%),AROM <12小时.
- 与较晚的AROM (>24小时:34.9%) 相比,早期AROM (13.9%) 的剖腹产率明显较低.
- 随着早期的AROM,孕产妇的发病率和从胚胎切割到分娩的时间减少了.
结论:
- 在宫成熟开始后12小时内进行胚胎切除并不会增加感染性发病率.
- 早期胚胎切除与减少传染性并发症,更短的分娩时间和降低孕产妇发病率有关.
- 这些发现支持在分娩诱导过程中考虑早些时候进行胚胎切除.
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