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Updated: Jan 10, 2026

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探索甲基酸盐的选择性布基胆酶抑制潜力:实验和计算研究

Antonija Jelčić1, Stanislava Talić2, Ilijana Odak2

  • 1Department of Organic Chemistry, University of Zagreb Faculty of Chemical Engineering and Technology, Marulićev Trg 19, HR-10 000, Zagreb, Croatia.

European journal of medicinal chemistry
|November 28, 2025
PubMed
概括

新型甲基化合物选择性抑制布基胆化酶 (BChE),为阿尔茨海默病 (AD) 提供了一个有前途的治疗策略. 化合物13显示出强大的BChE抑制,表现优于胺,并且在和体外显示出良好的安全性.

关键词:
在ADMET分析中,分析了ADMET.阿尔茨海默氏症的疾病是阿尔茨海默氏症.甲基胆酶抑制的抑制作用分子对接是分子对接.分子动力学模拟模型类碳酸酸盐是什么?结构活动关系结构活动关系

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