口腔微生物组作为起源和迁移的法医标记:来自代表性不足的人群的见解,尼日利亚
Nengi Ogbanga1, Andrew Nelson2, Darren Smith2
1Faculty of Health and Life Sciences, Applied Sciences, Northumbria University, Newcastle upon Tyne, UK; Research Centre for Field Archaeology and Forensic Taphonomy, School of Law and Policing, University of Lancashire, Preston, UK.
Forensic science international. Genetics
|November 28, 2025
概括
口腔微生物组可以识别地理来源和跟踪人类迁徙. 移民 移民是移民.
科学领域:
- 法医科学 法医科学
- 微生物学 微生物学
- 人口遗传学 人口遗传学
背景情况:
- 口腔微生物群受到环境和宿主因素的影响,为人类分析提供了潜在的潜力.
- 它在法医学中的实用性,特别是用于确定地理来源和跟踪人类迁移,正在调查中.
研究的目的:
- 评估口腔微生物组用于确定地理来源的预测能力,使用来自六个国家的样本.
- 通过对尼日利亚移民进行纵向研究,评估移民对口腔微生物组特征的影响.
- 提供关于口腔微生物组分析在法医调查中的适用性的见解.
主要方法:
- 使用高通量测序来分析口腔微生物组合.
- 机器学习模型被用来根据微生物概况预测地理来源.
- 一项纵向研究追踪了尼日利亚移民口腔微生物组的变化,持续了六个月.
主要成果:
- 发现不同的口腔微生物概况与研究的六个地理区域相关.
- 尼日利亚移民在移民后的口腔微生物组中出现了最初的变化.
- 移民的口腔微生物组概况在六个月后恢复到与尼日利亚当地人相似.
结论:
- 口腔微生物组显示出在地理来源归因方面的法医应用的巨大潜力.
- 口腔微生物组分析可以帮助追踪人类迁徙模式.
- 这些发现为法医调查提供了宝贵的情报.
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