菌菌的RIFINs的一个子集与严重疟疾风险的降低有关,并通过保留的结构动机通过LILRB1进行参与

Kokouvi Kassegne1, Hai-Mo Shen2, Shen-Bo Chen2

  • 1National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), National Health Commission of the People's Republic of China (NHC) Key Laboratory of Parasite and Vector Biology, World Health Organization (WHO) Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai, 200025, P. R. China; School of Global Health, Chinese Centre for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, P. R. China.

EBioMedicine
|November 28, 2025
PubMed
概括

研究人员确定了特定的RIFIN蛋白质,通过与LILRB1受体结合来降低严重疟疾风险. 这一发现为开发疟疾疫苗提供了新的策略,准保存的动机,以克服病原体多样性.

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