评价儿童健康:美国的EQ-5D-Y-3L值集
A Simon Pickard1, Jonathan L Nazari2, Juan M Ramos-Goñi3
1Department of Pharmacy Systems, Outcomes, and Policy, College of Pharmacy, University of Illinois Chicago, Chicago, Illinois, USA; Maths in Health B.V., Klimmen, The Netherlands.
概括
根据成人和青少年的偏好,为EQ-5D-Y-3L开发了一个新的美国价值设置. 该工具测量了与儿科健康相关的生活质量,并纳入利益相关者的意见以进行基于价值的评估.
科学领域:
- 卫生经济学 卫生经济学
- 心理测量 心理测量 心理测量
- 儿科健康结果的结果
背景情况:
- 测量儿科健康相关生活质量 (HRQoL) 对于评估医疗保健干预措施至关重要.
- 现有的价值观集可能无法完全捕捉到美国儿科患者群体的偏好.
- 利益相关方的参与对于制定相关的健康结果措施至关重要.
研究的目的:
- 为了开发一个美国的EuroQol5维青年版本,3级 (EQ-5D-Y-3L) 值集.
- 根据美国成人和青少年的偏好来测量儿科HRQoL.
- 为儿童提供医疗干预的基于价值的评估提供信息.
主要方法:
- 使用了EuroQol国际估值协议与美国利益相关者的建议.
- 通过在线离散选择实验 (DCE) 从美国成年人和青少年 (11-17岁) 收集数据.
- 成年人还完成了复合时间权衡 (cTTO) 任务;DCE数据对美国人口统计学进行了加权,并使用混合逻辑模型进行分析.
主要成果:
- 分析样本包括714名青少年和1669名成年人的DCE数据,以及199名成年人的cTTO数据.
- 估计的公用事业费用范围从0.079 (最差的状态) 到0.976 (最好的状态).
- 疼痛/不适和情绪困扰 (担心/悲伤/不快乐) 被确定为最具影响力的维度.
结论:
- 开发的美国EQ-5D-Y-3L值集解决了对儿科HRQoL评估的关键需求.
- 该价值集包含了青少年和成年人的偏好,提高了其适用性.
- 在美国利益相关者参与的基础上,该工具支持儿童医疗保健的基于价值的决策.
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