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Updated: Jan 10, 2026

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
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Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

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黑色素瘤细胞中的表型切换:MITF通过内部区域的E-box调节CDH1的表达

Evangeline Breeta Raja David Isac1, Sara Sigurbjörnsdóttir2, Ramile Dilshat3

  • 1BioMedical Center, Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.

The Journal of investigative dermatology
|November 28, 2025
PubMed
概括

黑色素瘤细胞切换表型以逃避治疗. 微相关转录因子 (MITF) 直接调节E-cadherin (CDH1) 表达,这是黑色素瘤表型切换过程中的关键步骤.

关键词:
CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1 CDH1美国MITF MITF黑色素瘤是一种黑色素瘤.现象型切换 现象型切换转录 转录 转录 转录

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