naringeninicaritin,Escherichia coli使prenol

Anyi Wu1, Junping Zhou2, Yinan Xue3

  • 1The National and Local Joint Engineering Research Center for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, PR China; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, PR China; State Key Laboratory of Green Chemical Synthesis and Conversion, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, PR China.

概括

研究人员对大肠杆菌 (Escherichia coli) 进行了基因工程,用于生产肝癌药物伊卡里 (ICT). 这种 prokaryotic 系统有效地将 naringenin 和 prenol 生物转化为 ICT,实现了高产量并为工业规模制造铺平了道路.

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