儿童腺切除术后阻断性睡眠障碍呼吸严重程度和疼痛轨迹之间的关联:一项前性队列研究
Chantal Frigon1, Ramanakumar V Agnihotram2, Annick Bérard-Giasson1
1Department of Anaesthesia, Division of Paediatric Anaesthesia, McGill University, Montreal, QC, Canada.
British journal of anaesthesia
|November 28, 2025
概括
患有严重阻塞性睡眠呼吸障碍 (oSDB) 的儿童往往会经历长时间的腺切除术后疼痛和更多的住院访问. 较高的oSDB严重程度与更严重的疼痛轨迹和更多的止痛药使用有关.
科学领域:
- 儿科外科手术 儿科外科手术
- 睡眠的药物 睡眠的药物
- 疼痛管理 疼痛管理
背景情况:
- 阻断性睡眠呼吸障碍 (oSDB) 与炎症有关,可能影响疼痛感知.
- 需要进一步调查oSDB严重程度和腺切除术后疼痛之间的关系.
研究的目的:
- 为了研究阻塞性睡眠呼吸障碍 (oSDB) 严重程度和腺切除术后疼痛之间的相关性.
- 分析与oSDB严重程度相关的止痛药使用率和医院复诊率.
主要方法:
- 对2至12岁接受腺切除术的儿童进行前性队列研究.
- 使用修改后的打,呼吸困难,未更新 (mSTBUR) 问卷进行评估的oSDB严重程度.
- 术后疼痛通过父母的术后疼痛测量 (PPPM) 和14天的止痛记录进行测量.
主要成果:
- 确定了三种不同的疼痛轨迹:轻度/短暂,中度和严重/长期.
- 较高的手术前mSTBUR得分与严重/持续的疼痛轨迹相关 (OR 0.52-0.58,P<0.05).
- 严重疼痛的儿童需要更多的止痛药,并且有显著更高的非预定的医院复诊几率 (OR 3.5-10.5,P<0.05).
结论:
- 腺切除术后的疼痛遵循可预测的轨迹,受到oSDB严重程度的影响.
- 患有严重oSDB的儿童面临更高的长期疼痛和重入医院的风险.
- oSDB评估可能有助于预测和管理术后疼痛.
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