计算建模和组织学分析6.78和2MHz单极无线电频率诱导的热反应
Kwangchon Ko1,2, Hye Guk Ryu1,2, Jinyoung Park1,2
1Cynosure Lutronic Corporation, Goyang, Korea, Republic of.
双频单极无线电频率 (RF) 通过增强皮肤和皮下皮肤中的原和弹性质重塑来提供卓越的皮肤再生. 这种先进的治疗方法有效地围绕着身体,同时保持脂肪细胞的活力,与单频方法不同.
科学领域:
- 皮肤病学 皮肤病学
- 生物医学工程 生物医学工程
- 审美医学是一种美学医学.
背景情况:
- 单极无线电频率 (RF) 设备用于皮肤收紧和身体轮是普遍存在的.
- 频率依赖的能量吸收和组织重塑的不充分表征限制了设备的最佳应用.
- 了解热分布和组织学反应对于推进射频治疗至关重要.
研究的目的:
- 为了比较6.78MHz和2MHz单极射频的热分布和组织学反应.
- 为了评估连续双频 (6.78MHz和2MHz) 射频应用的效果.
- 评估对细胞外矩阵重塑和脂肪细胞活力的影响.
主要方法:
- 用于电场和热扩散模拟的有限元计算建模.
- 在猪皮肤上的体内研究使用6.78MHz,2MHz和双频射频模式.
- 组织学分析 (H&E,马森三色素,Verhoeff-van Gieson) 和TUNEL测定细胞亡.
主要成果:
- 2MHz的射频在脂肪组织中诱导了更广泛,更深的热效应;6.78MHz的射频在纤维细分线上引起局部加热.
- 双频射频在皮肤下皮肤结处产生了明显的热反应.
- 在双频治疗的皮肤中观察到显著的原蛋白和弹性质重塑,维护了脂肪细胞的活力和增强了长期重塑.
结论:
- 双频单极射频促进皮肤和皮下皮肤的广泛的细胞外矩阵重塑.
- 这种方式有效地使皮肤再生,并轮身体,同时保持脂肪细胞的活力.
- 双频射频为先进的美容治疗提供了安全和多功能选择.
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