在后COVID-19时代 (2020-2024) 肝癌免疫疗法的研究进展和前沿趋势:基于文献计量方法的可视化分析
Shicai Liang1, Xusheng Zhang1, Xuebo Wang1
1Ningxia Medical University, Yinchuan, 750004, China.
Discover oncology
|November 28, 2025
概括
图书统计分析显示,中国和美国在COVID-19后领导肝癌免疫疗法研究. 关键主题包括瘤微环境和组合疗法,推动未来的临床基础翻译研究.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 图书统计学 图书统计学
背景情况:
- COVID-19大流行严重影响了肝癌研究,突出了晚期免疫疗法.
- 图书统计分析被用来绘制肝癌免疫疗法研究的不断变化的景观.
研究的目的:
- 确定从2020年到2024年肝癌免疫疗法的研究热点和范式转变.
- 分析全球研究趋势,合作和在该领域有影响力的出版物.
主要方法:
- 从科学网络核心集合 (2020-2024) 中对文献进行图书法分析.
- 使用了包括Biblioshiny,VOSviewer,Scimago Graphica和CiteSpace在内的工具进行数据分析.
- 通过严格的清洁来确保数据质量,达到0.89.8的卡帕系数.
主要成果:
- 中国和美国是领先的国家,其中包括加拿大的重要合作网络.
- 孙中山大学是一个主要的贡献者,与华中科技大学和江大学有着密切的联系.
- 主要研究主题包括预后模型,瘤微环境,肝细胞癌机制和癌症免疫疗法,以及"瘤微环境"和"组合疗法"的新兴趋势.
结论:
- COVID-19大流行加速了多学科整合和在肝癌免疫疗法研究中使用现实世界的证据.
- 中美合作,领先期刊的知识传播,以及对瘤微环境的关注,正在塑造未来的研究方向.
- 结果为资源优化和推进肝癌免疫疗法的临床基础翻译研究提供了战略见解.
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